Main content

Most Recent Journal Article


Iron(II)/(NH)2P2 Macrocycles: Modular, Highly Enantioselective Transfer Hydrogenation Catalysts

Complexes based on earth-abundant and nontoxic iron with an (NH)2 P2 macrocycle with a C3 bridge were applied as catalysts in the asymmetric transfer hydrogenation of polar double bonds. Thanks to the ligand modularity and to the use of tunable isonitriles as ancillary ligands, the catalyst system can be individually optimized for each substrate to give high enantioselectivity (up to 99.9% conversion and 99.6% ee, TOF up to >3950 h–1 ) for a broad scope of 26 substrates. Read more 

See more Articles and News on the Group News Page.

Page URL:
© 2017 Eidgenössische Technische Hochschule Zürich